Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD

Enzymes in the cytochrome P450 1 family oxidize many common environmental toxicants. We identified a new CYP1, termed CYP1D1, in zebrafish. Phylogenetically, CYP1D1 is paralogous to CYP1A and the two share 45% amino acid identity and similar gene structure. In adult zebrafish, CYP1D1 is most highly...

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Main Authors: Goldstone, J. V., Jönsson, M. E., Behrendt, L., Woodin, B. R., Jenny, M. J., Nelson, D. R., Stegeman, J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661202/
https://ncbi.nlm.nih.gov/pubmed/19103147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.12.002
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