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Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers

Cancer cell membrane proteins are released into the plasma/serum by exterior protein cleavage, membrane sloughing, cellular secretion or cell lysis, and represent promising candidates for interrogation. Because many known disease biomarkers are both glycoproteins and membrane bound, we chose the hyd...

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Detalhes bibliográficos
Main Authors: Whelan, Stephen A., Lu, Ming, He, Jianbo, Yan, Weihong, Saxton, Romaine E., Faull, Kym F., Whitelegge, Julian P., Chang, Helena R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761014/
https://ncbi.nlm.nih.gov/pubmed/19522481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900322g
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