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Extracellular Redox Modulation by Regulatory T Cells(†)

We demonstrate that the mechanism of redox remodeling during mouse T cell activation involves secretion of glutathione by dendritic cells and its subsequent cleavage to cysteine. Extracellular cysteine accumulation results in a lower redox potential, which is conducive to proliferation, and changes...

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Hlavní autoři: Yan, Zhonghua, Garg, Sanjay K, Kipnis, Jonathan, Banerjee, Ruma
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760945/
https://ncbi.nlm.nih.gov/pubmed/19718041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.212
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