Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase Cδ, Lyn Kinase, and Matrix Metalloproteinases

We have demonstrated earlier that lysophosphatidic acid (LPA)-induced interleukin-8 (IL-8) secretion is regulated by protein kinase Cδ (PKCδ)-dependent NF-κB activation in human bronchial epithelial cells (HBEpCs). Here we provide evidence for signaling pathways that regulate LPA-mediated transactiv...

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Detalhes bibliográficos
Main Authors: Zhao, Yutong, He, Donghong, Saatian, Bahman, Watkins, Tonya, Spannhake, Ernst Wm., Pyne, Nigel J., Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760938/
https://ncbi.nlm.nih.gov/pubmed/16687414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M511224200
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