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CCR5 Monoclonal Antibodies for HIV-1 Therapy

PURPOSE OF REVIEW: This report summarizes emerging clinical and preclinical data pertaining to the use of CCR5 monoclonal antibodies (mAbs) as therapies for HIV-1 infection. The epitope specificity of CCR5 mAbs is discussed in relation to its critical impact on antiviral activity and CCR5 antagonism...

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Hlavní autoři: Olson, William C., Jacobson, Jeffrey M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760828/
https://ncbi.nlm.nih.gov/pubmed/19339948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0b013e3283224015
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