Gnotobiotic IL-10(−/−); NF-κB(EGFP) Mice Develop Rapid and Severe Colitis Following Campylobacter jejuni Infection

Limited information is available on the molecular mechanisms associated with Campylobacter jejuni (C. jejuni) induced food-borne diarrheal illnesses. In this study, we investigated the function of TLR/NF-κB signaling in C. jejuni induced pathogenesis using gnotobiotic IL-10(−/−); NF-κB(EGFP) mice. I...

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Autores principales: Lippert, Elisabeth, Karrasch, Thomas, Sun, Xiaolun, Allard, Brigitte, Herfarth, Hans H., Threadgill, Deborah, Jobin, Christian
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760752/
https://ncbi.nlm.nih.gov/pubmed/19841748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007413
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