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DIFFERENTIAL ROLE OF NR2A AND NR2B NMDA RECEPTORS IN MEDIATING PHENCYCLIDINE-INDUCED PERINATAL NEURONAL APOPTOSIS AND BEHAVIORAL DEFICITS

The mechanism underlying PCP-induced apoptosis in perinatal rats and the development of schizophrenic-like behaviors is incompletely understood. We used antagonists for NR2A- and NR2B-containing NMDARs to test the hypothesis that the behavioral and apoptotic effects of PCP are mediated by blockade o...

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Main Authors: Anastasio, Noelle C., Xia, Yan, O’Connor, Zoe R., Johnson, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760688/
https://ncbi.nlm.nih.gov/pubmed/19654040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.07.058
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