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Lithium Protection of Phencyclidine-induced Neurotoxicity in Developing Brain: the Role of PI-3K/Akt and MEK/ERK Signaling Pathways

Phencyclidine (PCP) and other N-methyl-D-aspartate (NMDA) receptor antagonists have been shown to be neurotoxic to developing brains and to result in schizophrenia-like behaviors later in development. Prevention of both effects by antischizophrenic drugs suggests the validity of PCP neurodevelopment...

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Detalhes bibliográficos
Main Authors: Xia, Yan, Wang, Cheng Z, Liu, Jie, Anastasio, Noelle C., Johnson, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561310/
https://ncbi.nlm.nih.gov/pubmed/18544676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.133272
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