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Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1.

Nin1p, a component of the 26S proteasome of Saccharomyces cerevisiae, is required for activation of Cdc28p kinase at the G1-S-phase and G2-M boundaries. By exploiting the temperature-sensitive phenotype of the nin1-1 mutant, we have screened for genes encoding proteins with related functions to Nin1...

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Autors principals: Kominami, K, Okura, N, Kawamura, M, DeMartino, G N, Slaughter, C A, Shimbara, N, Chung, C H, Fujimuro, M, Yokosawa, H, Shimizu, Y, Tanahashi, N, Tanaka, K, Toh-e, A
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC276068/
https://ncbi.nlm.nih.gov/pubmed/9017604
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