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Conformational Cycle of the ABC transporter MsbA in Liposomes. Detailed Analysis using Double Electron-Electron Resonance Spectroscopy

Driven by the energy of ATP binding and hydrolysis, ATP binding cassette (ABC) transporters alternate between inward- and outward-facing conformations allowing vectorial movement of substrates. Conflicting models have been proposed to describe the conformational motion underlying this switch in acce...

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Autori principali: Zou, Ping, Bortolus, Marco, Mchaourab, Hassane S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760609/
https://ncbi.nlm.nih.gov/pubmed/19715702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.050
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