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Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously
BACKGROUND: Alterations in the number of copies of genomic DNA that are common or recurrent among diseased individuals are likely to contain disease-critical genes. Unfortunately, defining common or recurrent copy number alteration (CNA) regions remains a challenge. Moreover, the heterogeneous natur...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760535/ https://ncbi.nlm.nih.gov/pubmed/19775444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-308 |
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