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Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.

To identify components involved in nuclear protein import, we used a genetic selection to isolate mutants that mislocalized a nuclear-targeted protein. We identified temperature-sensitive mutants that accumulated several different nuclear proteins in the cytoplasm when shifted to the semipermissive...

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Publicat a:Mol Biol Cell
Autors principals: DeHoratius, C, Silver, P A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8930904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.11.1835
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