Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.
To identify components involved in nuclear protein import, we used a genetic selection to isolate mutants that mislocalized a nuclear-targeted protein. We identified temperature-sensitive mutants that accumulated several different nuclear proteins in the cytoplasm when shifted to the semipermissive...
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| Veröffentlicht in: | Mol Biol Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Cell Biology
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8930904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.11.1835 |
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