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Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

Fat metabolism, reproduction, and aging are intertwined regulatory axes; however, the mechanism by which they are coupled remains poorly understood. We found that germline stem cells (GSCs) actively modulate lipid hydrolysis in Caenorhabditis elegans, which in turn regulates longevity. GSC arrest pr...

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Detalles Bibliográficos
Main Authors: Wang, Meng C., O’Rourke, Eyleen J., Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760269/
https://ncbi.nlm.nih.gov/pubmed/18988854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162011
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