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Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
Fat metabolism, reproduction, and aging are intertwined regulatory axes; however, the mechanism by which they are coupled remains poorly understood. We found that germline stem cells (GSCs) actively modulate lipid hydrolysis in Caenorhabditis elegans, which in turn regulates longevity. GSC arrest pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760269/ https://ncbi.nlm.nih.gov/pubmed/18988854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162011 |
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