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Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes
p63, known to play a role in development, has more recently also been implicated in cancer progression. Mutations in p63 have been shown to be responsible for several human developmental diseases. Differential splicing of the p63 gene gives rise to p63 isoforms, which can act either as tumor suppres...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760224/ https://ncbi.nlm.nih.gov/pubmed/18626511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.82 |
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