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The HIV Envelope but Not VSV Glycoprotein Is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells

HIV fusion and entry into CD4 T cells are mediated by two receptors, CD4 and CXCR4. This receptor requirement can be abrogated by pseudotyping the virion with the vesicular stomatitis virus glycoprotein (VSV-G) that mediates viral entry through endocytosis. The VSV-G-pseudotyped HIV is highly infect...

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Detalhes bibliográficos
Main Authors: Yu, Dongyang, Wang, Weifeng, Yoder, Alyson, Spear, Mark, Wu, Yuntao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760144/
https://ncbi.nlm.nih.gov/pubmed/19851458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000633
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