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IL-21 and TGF-β are required for differentiation of human T(H)17 cells
The recent discovery of CD4(+) T cells characterized by secretion of interleukin (IL)-17 (T(H)17 cells) and the naturally occurring regulatory FOXP3(+) CD4 T cell (nT(reg)) has had a major impact on our understanding of immune processes not readily explained by the T(H)1/T(H)2 paradigm. T(H)17 and n...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760130/ https://ncbi.nlm.nih.gov/pubmed/18469800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07021 |
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