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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

On activation, naive T cells differentiate into effector T-cell subsets with specific cytokine phenotypes and specialized effector functions(1). Recently a subset of T cells, distinct from T helper (T(H))1 and T(H)2 cells, producing interleukin (IL)-17 (T(H)17) was defined and seems to have a crucia...

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Detalhes bibliográficos
Main Authors: Korn, Thomas, Bettelli, Estelle, Gao, Wenda, Awasthi, Amit, Jäger, Anneli, Strom, Terry B., Oukka, Mohamed, Kuchroo, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805028/
https://ncbi.nlm.nih.gov/pubmed/17581588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05970
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