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Nuclear NF-κB p65 phosphorylation at Serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer

PURPOSE: Aberrant nuclear activation and phosphorylation of the canonical NF-κB subunit RELA/p65 at Serine-536 by Inhibitor Kappa B Kinase is prevalent in head and neck squamous cell carcinoma (HNSCC), but the role of other kinases in NF-κB activation has not been well defined. Here, we investigated...

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Detalhes bibliográficos
Main Authors: Arun, Pattatheyil, Brown, Matthew, Ehsanian, Reza, Chen, Zhong, Van Waes, Carter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760015/
https://ncbi.nlm.nih.gov/pubmed/19789307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1352
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