Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex

The mutant Chinese hamster ovary cell line MT58 contains a thermosensitive mutation in CTP:phosphocholine cytidylyltransferase, the regulatory enzyme in the CDP-choline pathway. As a result, MT58 cells have a 50% decrease in their phosphatidylcholine (PC) level within 24 h when cultured at the nonpe...

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Bibliografiske detaljer
Main Authors: Testerink, Nicole, van der Sanden, Michiel H. M., Houweling, Martin, Helms, J. Bernd, Vaandrager, Arie B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759824/
https://ncbi.nlm.nih.gov/pubmed/19458387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800660-JLR200
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