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Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft.

We used random mutagenesis to create 21 point mutations in a highly conserved region of the motor domain of Dictyostelium myosin and classified them into three distinct groups based on the ability to complement myosin null cell phenotypes: wild type, intermediate, and null. Biochemical analysis of t...

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Bibliographische Detailangaben
Hauptverfasser: Ruppel, K M, Spudich, J A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC275963/
https://ncbi.nlm.nih.gov/pubmed/8862525
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