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Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft.

We used random mutagenesis to create 21 point mutations in a highly conserved region of the motor domain of Dictyostelium myosin and classified them into three distinct groups based on the ability to complement myosin null cell phenotypes: wild type, intermediate, and null. Biochemical analysis of t...

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Publicat a:Mol Biol Cell
Autors principals: Ruppel, K M, Spudich, J A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8862525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.7.1123
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