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DAZL Relieves miRNA-Mediated Repression of Germline mRNAs by Controlling Poly(A) Tail Length in Zebrafish

BACKGROUND: During zebrafish embryogenesis, microRNA (miRNA) miR-430 contributes to restrict Nanos1 and TDRD7 to primordial germ cells (PGCs) by inducing mRNA deadenylation, mRNA degradation, and translational repression of nanos1 and tdrd7 mRNAs in somatic cells. The nanos1 and tdrd7 3′UTRs include...

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Detalhes bibliográficos
Main Authors: Takeda, Yasuaki, Mishima, Yuichiro, Fujiwara, Toshinobu, Sakamoto, Hiroshi, Inoue, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759513/
https://ncbi.nlm.nih.gov/pubmed/19838299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007513
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