MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

Repression of mitochondrial respiration represents an evolutionarily ancient cellular adaptation to hypoxia and profoundly influences cell survival and function; however, the underlying molecular mechanisms are incompletely understood. Primarily utilizing pulmonary arterial endothelial cells as a re...

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Main Authors: Chan, Stephen Y., Zhang, Ying-Yi, Hemann, Craig, Mahoney, Christopher E., Zweier, Jay L., Loscalzo, Joseph
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759401/
https://ncbi.nlm.nih.gov/pubmed/19808020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.08.015
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