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In-column preparation of a brush-type chiral stationary phase using click chemistry and a silica monolith

Brush-type chiral stationary phases have been prepared both from a silica monolith and, separately, from 10 μm porous silica beads via a process of in-column modification including attachment of the chiral selector via copper catalyzed azide-alkyne cycloaddition. Azide functionalities were first int...

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Detalhes bibliográficos
Main Authors: Slater, Michael D., Fréchet, Jean M.J., Svec, Frantisek
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759375/
https://ncbi.nlm.nih.gov/pubmed/19051194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jssc.200800493
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