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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR de-repression checkpoint
Activation of Toll-Like Receptors (TLRs) leads to de-repression and subsequent activation of inflammatory response genes that play essential roles in innate and acquired immunity. De-repression requires signal-dependent turnover of the nuclear receptor corepressor NCoR from target promoters, but the...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759189/ https://ncbi.nlm.nih.gov/pubmed/19595715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.023 |
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