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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR de-repression checkpoint

Activation of Toll-Like Receptors (TLRs) leads to de-repression and subsequent activation of inflammatory response genes that play essential roles in innate and acquired immunity. De-repression requires signal-dependent turnover of the nuclear receptor corepressor NCoR from target promoters, but the...

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Détails bibliographiques
Auteurs principaux: Huang, Wendy, Ghisletti, Serena, Perissi, Valentina, Rosenfeld, Michael G., Glass, Christopher K.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759189/
https://ncbi.nlm.nih.gov/pubmed/19595715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.023
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