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Selective Covalent Bond Formation in Polypeptide Ions via Gas-Phase Ion/Ion Reaction Chemistry

[Image: see text] Primary amines present in protonated polypeptides can be covalently modified via gas-phase ion/ion reactions using bifunctional reagent ions. The use of reagent anions with a charge bearing site that leads to strong interactions with the polypeptide, such as sulfonic acid, gives ri...

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Autors principals: Han, Hongling, McLuckey, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759070/
https://ncbi.nlm.nih.gov/pubmed/19702304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904812d
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