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Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy
The epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor involved in the proliferation and survival of cancer cells. EGFR is the first molecular target against which monoclonal antibodies (mAb) have been developed for cancer therapy. Here we review the mechanisms under...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Blackwell Science Inc
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759052/ https://ncbi.nlm.nih.gov/pubmed/19737224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03992.x |
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