Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy

The epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor involved in the proliferation and survival of cancer cells. EGFR is the first molecular target against which monoclonal antibodies (mAb) have been developed for cancer therapy. Here we review the mechanisms under...

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Detalles Bibliográficos
Main Authors: Martinelli, E, De Palma, R, Orditura, M, De Vita, F, Ciardiello, F
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
Assuntos:
Review Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759052/
https://ncbi.nlm.nih.gov/pubmed/19737224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03992.x
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