Preimplantation genetic diagnosis for α-thalassaemia in China

PURPOSE: To report the usage of PGD for α-thalassaemia with the - -(SEA) genotype. METHOD: A PGD protocol using fluorescent gap PCR was performed for 51 cycles on 43 couples with the - -(SEA) genotype. Allele drop-out and amplification failure rates were retrospectively analyzed. RESULTS: A total of...

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Autori principali: Xu, Yan-Wen, Zeng, Yan-Hong, Deng, Jie, Liu, Ying, Gao, Ling, Zhou, Can-Quan, Zhuang, Guang-Lun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2009
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758951/
https://ncbi.nlm.nih.gov/pubmed/19813097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-009-9336-4
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