Preimplantation genetic diagnosis for α-and β-double thalassemia

PURPOSE: To evaluate the use of multiple displacement amplification (MDA) for preimplantation genetic diagnosis (PGD) of α- and β-double thalassemia. METHOD: Whole genome of a single cell was directly amplified using MDA and its products were used as templates in fluorescent gap polymerase chain rea...

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Bibliografiske detaljer
Main Authors: Shen, Xiaoting, Xu, Yanwen, Zhong, Yiping, Zhou, Canquan, Zeng, Yanhong, Zhuang, Guanglun, Ding, Chenhui, Li, Tao
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2011
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220442/
https://ncbi.nlm.nih.gov/pubmed/21667101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-011-9598-5
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