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Biochemical analysis of CTLA-4 immunoreactive material from human blood

BACKGROUND: CTLA-4 was initially described as a membrane-bound molecule that inhibited lymphocyte activation by interacting with B7.1 and B7.2 molecules on antigen presenting cells. Alternative splicing of mRNA encoding the CTLA-4 receptor leads to the production of a molecule (sCTLA-4) that lacks a...

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Autori principali: Tector, Matt, Khatri, Bhupendra O, Kozinski, Karen, Dennert, Kate, Oaks, Martin K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758829/
https://ncbi.nlm.nih.gov/pubmed/19772653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-51
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