Differential inhibition of autoreactive memory- and alloreactive naive T cell responses by soluble cytotoxic T lymphocyte antigen 4 (sCTLA4), CTLA4Ig and LEA29Y

Cytotoxic T lymphocyte antigen 4 (CTLA4) is a potent inhibitory co-stimulatory molecule believed to be involved in type 1 diabetes and other autoimmune diseases. An association has been reported of both mRNA expression and serum levels of the soluble splice variant of CTLA4 (sCTLA4) with type 1 diab...

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Hlavní autoři: Huurman, V A L, Unger, W W J, Koeleman, B P C, Oaks, M K, Chandraker, A K, Terpstra, O T, Roep, B O
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2007
Témata:
Translational Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219382/
https://ncbi.nlm.nih.gov/pubmed/17924973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03513.x
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