Identification of an additional negative regulatory region for p53 sequence-specific DNA binding
The DNA binding activity of p53 is crucial for its tumor suppressor function and is subject to tight regulation. Previous studies revealed that the inhibitory function of the p53 C terminus is implicated in the latent, low affinity sequence-specific DNA binding activity of p53 in the uninduced state...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6079 |
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