The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes

Cohesins mediate sister chromatid cohesion and DNA repair and also function in gene regulation. Chromosomal cohesins are distributed nonrandomly, and their deposition requires the heterodimeric Scc2/Scc4 loader. Whether Scc2/Scc4 establishes nonrandom cohesin distributions on chromosomes is poorly c...

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Main Authors: Kogut, Igor, Wang, Jianbin, Guacci, Vincent, Mistry, Rohinton K., Megee, Paul C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758738/
https://ncbi.nlm.nih.gov/pubmed/19797771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1819409
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