Testosterone’s Short-Term Positive Effect on Luteinizing-Hormone Secretory-Burst Mass and Its Negative Effect on Secretory-Burst Frequency Are Attenuated in Middle-Aged Men

Background: Testosterone (T) production declines and LH pulses become smaller and more frequent in middle-aged men. The mechanisms underlying these changes are not known. Rationale: Small frequent LH pulses in middle-aged men could reflect impaired feedback by systemic T. Hypothesis: Middle age disr...

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Главные авторы: Liu, Peter Y., Takahashi, Paul Y., Roebuck, Pamela D., Bailey, Joy N., Keenan, Daniel M., Veldhuis, Johannes D.
Формат: Artigo
Язык:Inglês
Опубликовано: The Endocrine Society 2009
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758726/
https://ncbi.nlm.nih.gov/pubmed/19584190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-0135
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