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A simple and efficient algorithm for genome-wide homozygosity analysis in disease
Here we propose a simple statistical algorithm for rapidly scoring loci associated with disease or traits due to recessive mutations or deletions using genome-wide single nucleotide polymorphism genotyping case–control data in unrelated individuals. This algorithm identifies loci by defining homozyg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758715/ https://ncbi.nlm.nih.gov/pubmed/19756043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.53 |
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