A simple and efficient algorithm for genome-wide homozygosity analysis in disease

Here we propose a simple statistical algorithm for rapidly scoring loci associated with disease or traits due to recessive mutations or deletions using genome-wide single nucleotide polymorphism genotyping case–control data in unrelated individuals. This algorithm identifies loci by defining homozyg...

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Autors principals: Liu, Wei, Ding, Jinhui, Gibbs, Jesse Raphael, Wang, Sue Jane, Hardy, John, Singleton, Andrew
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758715/
https://ncbi.nlm.nih.gov/pubmed/19756043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.53
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