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Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease that affects ∼2/100 000 individuals each year worldwide. Patients with ALS suffer from rapidly progressive degeneration of motor neurons ultimately leading to death. The major pathological features observed in post-mor...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758707/ https://ncbi.nlm.nih.gov/pubmed/19808791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp303 |
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