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TLR5 Ligation by Flagellin Converts Tolerogenic Dendritic Cells into Activating Antigen-Presenting Cells that Preferentially Induce T-Helper 1 Responses
Dendritic cells (DCs) differentiated in the presence of IL-10 preferentially induce regulatory T-cells and tolerance. Whether the tolerogenic properties displayed by these DCs (Tol-DCs) can be overcome has not been fully explored. Here we show for the first time that Tol-DCs express higher levels of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758552/ https://ncbi.nlm.nih.gov/pubmed/19555720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2009.06.007 |
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