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Acquisition of suppressive function by activated human CD4(+) CD25(-) T cells is associated with the expression of CTLA-4 not FoxP3
The role of CTLA-4 in Regulatory T cell (Treg) function is not well understood. We have examined the role of CTLA-4 and its relationship with the transcription factor FoxP3 using a model of Treg induction in human peripheral blood. Activation of human CD4(+)CD25(-) T cells resulted in the appearance...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758479/ https://ncbi.nlm.nih.gov/pubmed/18641304 |
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