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Sequential Molecular Changes during Multistage Pathogenesis of Small Peripheral Adenocarcinomas of the Lung

INTRODUCTION: We investigated EGFR and KRAS alterations among atypical adenomatous hyperplasia and small lung adenocarcinomas with bronchioloalveolar features to understand their role during multistage pathogenesis. METHODS: Sixty lesions measuring 2 cm or less were studied, including 38 noninvasive...

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Main Authors: Soh, Junichi, Toyooka, Shinichi, Ichihara, Shuji, Asano, Hiroaki, Kobayashi, Naruyuki, Suehisa, Hiroshi, Otani, Hiroki, Yamamoto, Hiromasa, Ichimura, Kouichi, Kiura, Katsuyuki, Gazdar, Adi F., Date, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758162/
https://ncbi.nlm.nih.gov/pubmed/18379350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318168d20a
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