Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem cell–like Properties in Cancer Cells

Acquired resistance to EGF receptor (EGFR) tyrosine kinase inhibitor (TKI) is a critical problem in the treatment of lung cancer. Although several mechanisms have been shown to be responsible for acquired resistance, all mechanisms have not been uncovered. In this study, we investigated the molecula...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Shien, Kazuhiko, Toyooka, Shinichi, Yamamoto, Hiromasa, Soh, Junichi, Jida, Masaru, Thu, Kelsie L., Hashida, Shinsuke, Maki, Yuho, Ichihara, Eiki, Asano, Hiroaki, Tsukuda, Kazunori, Takigawa, Nagio, Kiura, Katsuyuki, Gazdar, Adi F., Lam, Wan L., Miyoshi, Shinichiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506773/
https://ncbi.nlm.nih.gov/pubmed/23542356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4136
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