Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem cell–like Properties in Cancer Cells

Acquired resistance to EGF receptor (EGFR) tyrosine kinase inhibitor (TKI) is a critical problem in the treatment of lung cancer. Although several mechanisms have been shown to be responsible for acquired resistance, all mechanisms have not been uncovered. In this study, we investigated the molecula...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Shien, Kazuhiko, Toyooka, Shinichi, Yamamoto, Hiromasa, Soh, Junichi, Jida, Masaru, Thu, Kelsie L., Hashida, Shinsuke, Maki, Yuho, Ichihara, Eiki, Asano, Hiroaki, Tsukuda, Kazunori, Takigawa, Nagio, Kiura, Katsuyuki, Gazdar, Adi F., Lam, Wan L., Miyoshi, Shinichiro
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506773/
https://ncbi.nlm.nih.gov/pubmed/23542356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4136
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