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Reversal of Chemoresistance and Enhancement of Apoptosis by Statins Through Downegulation of the NF-κB pathway

We recently found that simvastatin can modulate the nuclear factor-κB (NF-κB) activation pathway, but whether other statins have similar effects to those of simvastatin is unknown. Therefore, we evaluated the effect six different statins on TNF-induced NF-κB activation in human myeloid leukemia cell...

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Autores principales: Ahn, Kwang Seok, Sethi, Gautam, Aggarwal, Bharat B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757941/
https://ncbi.nlm.nih.gov/pubmed/18036510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.10.010
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