An amino acid as a cofactor for a catalytic polynucleotide
Natural ribozymes require metal ion cofactors that aid both in structural folding and in chemical catalysis. In contrast, many protein enzymes produce dramatic rate enhancements using only the chemical groups that are supplied by their constituent amino acids. This fact is widely viewed as the most...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6027 |
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