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An amino acid as a cofactor for a catalytic polynucleotide

Natural ribozymes require metal ion cofactors that aid both in structural folding and in chemical catalysis. In contrast, many protein enzymes produce dramatic rate enhancements using only the chemical groups that are supplied by their constituent amino acids. This fact is widely viewed as the most...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Roth, Adam, Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6027
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