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Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons
Fragile X syndrome is caused by lack of the protein FMRP. FMRP mediates mRNA binding, dendritic mRNA transport and translational control at spines. We examined the role of functional domains of FMRP in neuronal RNA-granule formation and dendritic transport using different FMRP variants, including th...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757577/ https://ncbi.nlm.nih.gov/pubmed/19464371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.05.004 |
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