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Both actin and polyproline interactions of Profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells

The objective of the present study was to evaluate how different ligand interactions of profilin-1 (Pfn1), an actin-binding protein that is upregulated during capillary morphogenesis of vascular endothelial cells (VEC), contribute to migration and capillary forming ability of VEC. We adopted a knock...

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Main Authors: Ding, Zhijie, Gau, David, Deasy, Bridget, Wells, Alan, Roy, Partha
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757537/
https://ncbi.nlm.nih.gov/pubmed/19607826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.07.004
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