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CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

Previous studies have shown that depletion of CD8+ cells during acute and chronic simian immunodeficiency virus (SIV) infection leads to increased viral replication, morbidity and mortality which have been attributed to loss of CD8+ T cell-mediated control of SIV virus. However, these studies did no...

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Main Authors: Mueller, Yvonne M., Do, Duc H., Boyer, Jean D., Kader, Muhamuda, Mattapallil, Joseph J., Lewis, Mark G., Weiner, David B., Katsikis, Peter D.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757467/
https://ncbi.nlm.nih.gov/pubmed/19786539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900141
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